A Randomized Placebo-Controlled Trial of D-Cycloserine for the Enhancement of Social Skills Training in Pervasive Development Disorders

Abstract

The main objective of this application is to determine whether D-cycloserine (DCS) can enhance the efficacy of social skills training (SST) in the treatment of children and young adolescents with autism spectrum disorders (ASDs). We will evaluate the efficacy, tolerability, and last effects of DCS given one hour prior to each of 10 weekly SST sessions for the treatment of social impairment in 68 children and young adolescents (ages 5-11 years) with ASDs during a randomized placebo-controlled trial. The safety and tolerability of DCS and durability of treatment response will also be examined.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2015
Accession Number
AD1003209

Entities

People

  • Marjorie Mccaskey
  • Noha Minshawi-patterson

Organizations

  • Indiana University Health

Tags

DTIC Thesaurus Topics

  • Age Groups
  • Anxiety Disorders
  • Autism
  • Data Analysis
  • Diseases And Disorders
  • Health Services
  • Human Behavior
  • Information Science
  • Institutional Review Board
  • Language
  • Medical Personnel
  • Mental Disorders
  • Psychiatry
  • Psychotherapy
  • Rehabilitation
  • Therapy
  • Training

Fields of Study

  • Medicine
  • Psychology

Readers

  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.