EMERGE: Engineered Materials that Create Environments for ReGeneration via Electric Field
Abstract
The report herein describes progress made in the first year of EMERGE: Engineered Materials the Create Environments for ReGeneration via Electric Fields. The objective of the project is to develop a next-generation ocular implant material with biomimetic chemistry and nanotopography with unique drug delivery functionality to 1) provide appropriate biochemical and biophysical cues for enhanced cell migration, differentiation and proliferation and 2) deliver wound electric field enhancing pharmaceuticals for enhanced bioelectronics cues. To this end, we are developing a collagen material with tailored nanotopography with ability to deliver endogenous wound electric field-enhancing molecules that will encourage and accelerate the wound healing process. We monitor wound electrophysiology as a function of time using a vibrating probe.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2015
- Accession Number
- AD1003263
Entities
People
- Brian Reid
- Lance Baird
- Leslie Hamilton
- Min Zhao
- Morgana Trexler
- Xiomara Caderon-colon
Organizations
- Johns Hopkins University Applied Physics Laboratory