Extraction Methodological Contributions Toward Ultra-Performance Liquid ChromatographyTime-of-Flight Mass Spectrometry: Quantification of Free GB from Various Food Matrices
Abstract
Liquid chromatographyelectrospray ionization mass spectrometry with positive-ion modes of operation were used for the trace-level determination of isopropyl methylphosphonofluoridate (sarin, GB) in various food matrices. The development of a solid-phase extraction method using a normal-phase silica gel column for extraction of GB in foodstuffs is described. GB concentrations ranging from 50 ng/mL to 1.2 g/mL were spiked into food samples. The linear range of quantitation was 0.31.2 g/mL for GB. The total percent recoveries (and percent relative standard deviations) for GB in various food samples are reported.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 2016
- Accession Number
- AD1004032
Entities
People
- Mark D Winemiller
- Sue Y. Bae
Organizations
- Edgewood Chemical Biological Center