Identifying Immune Drivers of Gulf War Illness Using a Novel Daily Sampling Approach

Abstract

The major aim of this research project is to identify aspects of the immune system that are dysregulated in veterans with Gulf War Illness. A second aim is to determine whether identified immune system dysregulations are similar to those found in men with fibromyalgia. To accomplish those aims at UAB, we are recruiting 29 male veterans diagnosed with Gulf War Illness (GWI), as well as 2 healthy veteran controls, and 4 males with Fibromyalgia/Chronic Fatigue Syndrome (FM/CFS). Participants will complete 25 consecutive days of blood draws and provide daily reports of symptom severity. Analyses will then be conducted to identify immune system factors that correlate with day-to-day symptom fluctuations in the participants. Ultimately,this information may be used to develop new treatments that specifically target the pathophysiological mechanisms of Gulf War Illness.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1004926

Entities

People

  • Jarred Younger
  • Lisa Smoot
  • Luke Parkitny

Organizations

  • University of Alabama at Birmingham

Tags

DTIC Thesaurus Topics

  • Biological Factors
  • Blood
  • Cardiovascular System
  • Cells
  • Chronic Fatigue Syndrome
  • Cytokines
  • Data Analysis
  • Data Sets
  • Diseases And Disorders
  • Health Services
  • Hematologic Tests
  • Immune System
  • Lymphocytes
  • Medical Personnel
  • Persian Gulf Syndrome
  • Proteins

Readers

  • Clinical Trial Research.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.