An in Vivo Investigation of Brain Inflammation in Gulf War Illness with Integrated PET/MR Imaging

Abstract

This project is aimed at evaluating the contribution of brain glia to the pathophysiology of Gulf War Illness, as well as fibromyalgia (a functional pain disorder characterized by similar symptoms). So far we have completed administrative and regulatory review, and have begun subject enrollment. The first two participants have completed the study. An additional three participants were enrolled and found to be ineligible at the time of screening. Throughout the recruitment process, we have actively modified our inclusion criteria to address concerns of ambiguity as they have arisen. Recruitment has been slower than anticipated, but efforts are well underway to improve recruitment procedures. Additionally, we experienced recent delays as a result of the Martinos Center cyclotron undergoing repair for more than one month. However, the resolution of these hurdles is in sight, and we are confident that well soon be able to increase our recruitment rate and successfully complete the project within the expected timeframe.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1005089

Entities

People

  • Marco L Loggia

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Brain
  • Diseases And Disorders
  • Health Services
  • Medical Personnel
  • Neuroglia
  • Neuromuscular Diseases
  • Pain
  • Peripheral Nervous System
  • Persian Gulf Syndrome

Readers

  • Clinical Trial Research.
  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Medical Imaging.