Genetic Alterations in Prostate Cancers among African-American Men and Comparisons with Cancers from European and Asian Patients

Abstract

Prostate cancer (PCa) research is lacking in the area of genetic epidemiology, particularly as it relates to African American men, who are 50 percent more likely to develop PCa than white men. Furthermore, more research is needed to be able to distinguish aggressive from non-aggressive PCa, especially at early stages. This study seeks to identify genetic alterations in African American men that are associated with aggressive and lethal PCa. Our secondary goal is to develop a cost-effective genetic test to better identify men at heightened risk of developing PCa, which will allow for earlier detection of disease and more effective treatment.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1006439

Entities

People

  • Jianfeng Xu

Tags

DTIC Thesaurus Topics

  • African Americans
  • Biomedical Research
  • Department Of Defense
  • Diseases And Disorders
  • Electronic Mail
  • Health
  • Health Services
  • High Resolution
  • Information Operations
  • Neoplasms
  • Patent Applications
  • Professional Development
  • Prostate
  • Prostate Cancer
  • Standards
  • Technology Transfer
  • Universities

Readers

  • Molecular and genetic basis of cancer.
  • Oncology
  • Prostate Cancer Biology.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech