3,3'-Dioctadecyloxacarbocyanine perchlorate (DiO) as a Fluorogenic Probe for Measurement of Critical Micelle Concentration

Abstract

Critical micelle concentration (CMC) is a key factor in applications of amphiphilic molecules, as it dictates the assembly state of the molecules. Nile Red (NR) is often used as a fluorogenic dye for the measurement of CMC values, but we have observed that NR is prone to aggregation, which leads to reduced reliability in CMC measurements. Here we evaluate 3,3'-dioctadecyloxacarbocyanine perchlorate (DiO) as an alternative fluorogenic dye for the measurement of CMC values. Both NR and DiO provide values comparable to those reported in the literature. However, we demonstrate that DiO provides improved consistency and is more user friendly than NR for measurement of CMC values.

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Document Details

Document Type
Technical Report
Publication Date
Jul 22, 2015
Accession Number
AD1006966

Entities

People

  • Amberlyn M. Peterson
  • Evelyn M. Kimbrough
  • Jennifer M. Heemstra
  • Zhesen Tan

Organizations

  • University of Utah

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Accuracy
  • Assembly
  • Chemistry
  • Consistency
  • Dyes
  • Emission
  • Emission Spectra
  • Fluorescence
  • Hydrophobic Properties
  • Incubation
  • Intensity
  • Light Scattering
  • Literature
  • Measurement
  • Military Research
  • Molecules
  • User Friendly

Readers

  • Molecular Genetics
  • Nanocomposite Materials Science
  • Regression Analysis.