Evaluation of the Safety and Efficacy of the FAAH Inhibitor URB597

Abstract

The award was to fund a 3-year program involving a phase I study to determine the safety, tolerability, and pharmacokinetics of orally administered URB597, the first potent and selective FAAH inhibitor, in healthy volunteers and a phase II study to determine the efficacy and safety of URB compared with placebo. Due to the Principal Investigators leaving the institution in March of 2015 the study was discontinued prior to the preclinical evaluations for pharmacokinetics and toxicology. The supply of URB597 that had been produced was shipped to the Uniformed Services University (USU) as instructed by USAMRMC, August 2015.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2016
Accession Number
AD1007397

Entities

People

  • Alexander Neumeister
  • Anthony Carna
  • Charles Marmar

Organizations

  • New York University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anxiety Disorders
  • Clinical Trials
  • Contracts
  • Diseases And Disorders
  • Inhibitors
  • Instructors
  • Medical Personnel
  • Mental Disorders
  • Neuroimaging
  • New York
  • Pharmacokinetics
  • Psychiatry
  • Test And Evaluation
  • Toxicology
  • Traumatic Stress Disorder
  • Universities

Fields of Study

  • Medicine

Readers

  • Oncology
  • Oncology (Cancer Research).
  • Political Science/ International Relations/ European Studies