Treatment of Early Post-op Wound Infection after Internal Fixation

Abstract

Severe fractures are common in modern warfare with fractures being fixed via internal fixation of plates and screws to hold the fracture stable while the bone heals. Approximately 10%-40% of severe fractures fixed with internal fixation develop a deep wound infection during the healing process. Thus, the overall goals of this study are to (1) evaluate the effect of treatment of post-op wound infection in long bones after fracture fixation or joint fusion and either: (Group 1) operative debridement and PO antibiotic treatment for 6 weeks; or (Group 2) operative debridement and IV antibiotics for 6 weeks and (2) build and validate a risk prediction model for failure of treatment of early postoperative wound infections after fixation of fractures or joint fusion.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1007576

Entities

People

  • William Obremskey

Organizations

  • Vanderbilt University Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Adhesion
  • Anti-Bacterial Agents
  • Biomedical Research
  • Bone Fractures
  • Debridement
  • Department Of Defense
  • Diseases And Disorders
  • Infection
  • Infectious Diseases
  • Information Operations
  • Orthopedic Surgical Procedures
  • Public Health
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.