Obesity/Overweight in Persons with Early and Chronic SCI: A Randomized Multi-Center Controlled Lifestyle Intervention

Abstract

The overarching study objective is to reduce health hazards from an overweight/obese body habitus and co-morbid cardiometabolic disorders in people with SCI, and to improve their life quality. The study is a four-year multi-center randomized clinical trial (RCT) conducted at 2 SCI rehabilitation research centers and two Veterans Affairs Medical Centers. The study is modeled after the Diabetes Prevention Program (DPP), an NIH-sponsored 27-center RCT that reported a sustained 7% body weight reduction in pre-diabetic individuals accompanied by a 58% decrease in progression to type-2 diabetes. The lifestyle intervention approach incorporating diet, exercise, and behavioral adjustments was more effective than pharmacotherapy, benefited both genders and persons of all races, and has lasted 10 years after initiation.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2011
Accession Number
AD1008136

Entities

People

  • Mark S. Nash

Organizations

  • University of Miami

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Birds
  • Body Weight
  • Fish
  • Fungi
  • Health Services
  • Medical Personnel
  • Vegetables

Fields of Study

  • Medicine

Readers

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