Hibernation-Based Therapy to Improve Survival of Severe Blood Loss

Abstract

The goals of this set experiments was to determine whether different concentrations of melatonin and DMSO along with 4M BHB would be as effective as our standard dosing regimen of 4M BHB/43mM Melatonin 20 DMSO. Based on the data presented data, our standard dosing regimen is the most effective treatment when compared to lower concentrations of melatonin DMSO in 4M BHB.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2015
Accession Number
AD1008267

Entities

People

  • Andrea Wolf
  • Gregory Beilman
  • Kristine Muller
  • Sydne Muratore

Organizations

  • Regents of the University of Minnesota

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biological Sciences
  • Biomedical Research
  • Blast Injuries
  • Blood
  • Data Analysis
  • Department Of Defense
  • Electronic Mail
  • Hemorrhagic Shock
  • Melatonin
  • Military Personnel
  • Resuscitation
  • Standards
  • Survival
  • Therapy
  • Torpor

Fields of Study

  • Physics

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Defense Acquisition Program Management
  • Trauma Surgery or Emergency Medicine.