Neuroprosthetics and Solutions for Restoring Sensorimotor Functions

Abstract

This project is focused on the development of a radically new class of prosthetic devices that will mimic more closely the full range of sensory and motor capabilities of natural limbs. To this end, we have made initial progress on four integrated projects to advance the development of neuroprosthetic limbs including: 1) creation of a sensory neural interface to provide amputees with tactile and kinesthetic feedback from their prosthetic limb, 2) improving the biocompatibility of implanted neural interface electrodes, 3) development of a virtual reality training and testing system for neuroprosthetic limbs, and 4) development of prosthetic hardware testing equipment and procedures. To date, we have completed pilot experiments to characterize the organization of sensory neurons in the DRG for the creation of a sensory feedback neural interface and evaluated the brains response to sensory stimulation. We have completed pilot experiments to evaluate histologically the tissue response to electrodes implanted chronically in DRG, dorsal roots, and spinal cord. We have designed and developed a virtual reality training system based on BCI2000, creating custom software to greatly extend the functionality of BCI2000. Finally, we have developed a test jig to determine compliance with ISO standards for prosthetic hardware, and we have begun testing prosthetic feet.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2009
Accession Number
AD1008449

Entities

People

  • Carl Lagenaur
  • Douglas J Weber
  • Rory A. Cooper
  • Tracy Cui
  • Wei Wang

Organizations

  • University of Pittsburgh

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Amputees
  • Biomedical Engineering
  • Carbon Nanotubes
  • Cells
  • Heart Rate
  • Medical Personnel
  • Nervous System
  • Neuroglia
  • Neurons
  • Peripheral Nervous System
  • Prostheses And Implants
  • Prosthetics
  • Residual Limbs
  • Spinal Cord
  • Surgical Amputations
  • Upper Limb Amputees
  • Virtual Reality

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Rehabilitation and Prosthetic Care for Military Service Members and Veterans with Limb Loss or Disability.
  • Robotics and Automation.