Intranasal Oxytocin for the Treatment of Pain Associated with Interstitial Cystitis

Abstract

The purpose of this study was to evaluate the efficacy of intranasal oxytocin on bladder nociception in a cohort of patients with interstitial cystitis (IC). We hypothesized that patients with IC are more likely to experience treatment responses as defined by global response assessment (GRA) scores when they receive intranasal oxytocin as opposed to when they receive intranasal saline. Secondary outcome measures included a verbal pain report (VPR; 0-10 with 0 being no pain and10 being the worst possible pain), a verbal anxiety report (VAR; 0-10 with 0 being no anxiety and 10 being the worst possible anxiety), number of voids since last contact with an investigator, and interim medications used for pain control or anxiety. Compared to saline administration intranasal oxytocin did not significantly decrease anxiety, pain or the number of voids reported by participants.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2015
Accession Number
AD1009877

Entities

People

  • Meredith T. Robbins

Organizations

  • University of Alabama at Birmingham

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  • African Americans
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  • Chronic Fatigue Syndrome
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  • Medicine
  • Psychology

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