The Disposition of Topically Applied Agents
Abstract
The topical route of administration of drugs is usually employed for the treatment of skin disorders. However, some of these preparations can penetrate through the skin and exert systemic effects. The disposition of topically applied agents is being studied at both the basic research and the clinical level. The research is aimed at elucidating the processes of absorption into and metabolism by the skin as well as the disposition of these agents and/or their metabolites systemically. New, noninvasive drug delivery systems are being considered and developed to employ topical agents systemically under special circumstances.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 24, 1981
- Accession Number
- AD1010628
Entities
People
- Nancy Stambler
Organizations
- Uniformed Services University of the Health Sciences