Time Course of Immune Activity in Response to Two Acute Stressors
Abstract
A number of studies have examined the effects of acute laboratory stressors on measures of immune system activity, reporting variable and sometimes contradictory results. We collected immune measures at four times during and following two common laboratory stressors (mental arithmetic with harassment and cold pressor) to temporally examine immune response patterns to these stressors. The six-minute stressor period was associated with increased self-report of pain and distress in both groups, as well as increased SBP, DBP and HR in the mental arithmetic group. Increased NK activity in this group was observed at 2 and 5minutes into the task and at 5 minutes after the task. The cold pressor group exhibited a marginal increase in NK activity 2 minutes into the task. A significant group x time effect was observed on lymphocyte proliferation to three concentrations of pokeweed mitogen.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 14, 1994
- Accession Number
- AD1011333
Entities
People
- Douglas L. Delahanty
Organizations
- Uniformed Services University of the Health Sciences