Adherence of Enterohemorrhagic Escherichia coli to Human Epithelial Cells: The Role of Intimin

Abstract

Enterohemorrhagic E.coli (EHEC) is the leading cause of infectious bloody diarrhea in the United States as well as acute renal failure among U.S. and Canadian children. EHEC colonize the large bowel and produce Shiga-like toxins (SLTs) that are considered essential for EHEC virulence. EHEC cause intestinal attaching and effacing (A/E) lesions in experimental animals and carry a homologue of the enteropathogenic E. coli (EPEC) eaeA (E. coli attach and efface) locus.

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Document Details

Document Type
Technical Report
Publication Date
Apr 28, 1995
Accession Number
AD1011453

Entities

People

  • Marian L Mckee

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Bacteria
  • Bacterial Infections
  • Blood
  • Cell Membrane
  • Cells
  • Cellular Structures
  • Chemistry
  • Coliphages
  • Dna Sequence Analysis
  • Epithelial Cells
  • Escherichia Coli
  • Fungi
  • Medical Personnel
  • Microbiology
  • Mucous Membrane
  • Sodium Compounds

Readers

  • Microbial Pathology