Trinitrobenzenesulfonic Acid Colitis Induces Changes in the Contractile Response of Circular Smooth Muscle in the Distal Colon
Abstract
Diarrhea is a common symptom of colitis. Alterations in colonic muscle contractility, through both neural and smooth muscle mechanisms, contribute to the abnormal motility patterns associated with inflammatory bowel disease. Changing inflammatory milieu may cause stage-dependent alterations of the muscle contractile response. The aim was to study colonic circular smooth muscle response to acetylcholine and the tachykinins during acute and chronic inflammation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 27, 1996
- Accession Number
- AD1011516
Entities
People
- Jeanette M. Hosseini
Organizations
- Uniformed Services University of the Health Sciences