Reprogramming Intestinal Immunity by Novel L. Acidophilus Strains Results in Protective Immunity against Colon Cancer

Abstract

Colorectal cancer (CRC) is the most common malignancy with high mortality worldwide and is also the 2nd most commoncause of cancer deaths in the United States despite important advances in detection, surgery and chemotherapy. Animbalance of commensal bacteria and their gene products underlie mucosal and, in particular, gastrointestinal (GI)inflammation and the predisposition to cancer. [Truncated]

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2015
Accession Number
AD1011789

Entities

People

  • Mansour Mohamadzadeh

Organizations

  • University of Florida

Tags

DTIC Thesaurus Topics

  • Antineoplastic Agents
  • Biomedical Research
  • Cancer
  • Cells
  • Colon
  • Colon Cancer
  • Epithelial Cells
  • Immunity
  • Intestines
  • Lymph Nodes
  • Lymphocytes
  • Microbiomes
  • Molecules
  • Neoplasms
  • Proteins
  • Regulations
  • Small Intestine

Fields of Study

  • Medicine

Readers

  • Microbial Pathology
  • Oncology (Cancer Research).