Genetic Characterization of Spondweni and Zika Viruses and Susceptibility of Geographically Distinct Strains of Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus (Diptera: Culicidae) to Spondweni Virus

Abstract

Zika virus (ZIKV) has extended its known geographic distribution to the Western Hemisphere and is now responsible for severe clinical complications in a sub-set of patients. While substantial genetic and vector susceptibility data exist for ZIKV, less is known for its sister flavivirus, Spondweni virus (SPONV). Both ZIKV and SPONV have been known to circulate in Africa since the mid-1900s, but neither has been genetically characterized by gene and compared in parallel. Furthermore, the susceptibility of cosmopolitan mosquito species incriminated or suspected in the transmission of ZIKV to SPONV was unknown.

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Document Details

Document Type
Technical Report
Publication Date
Oct 26, 2016
Accession Number
AD1012542

Entities

People

  • Alongkot Ponlawat
  • Andrew D. Haddow
  • Farooq Nasar
  • Hilda Guzman
  • Richard G Jarman
  • Robert B. Tesh
  • Scott C. Weaver

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Africa
  • Amino Acids
  • Arboviruses
  • Blood Substitutes
  • Diseases And Disorders
  • East Africa
  • Genetic Code
  • Geographic Distribution
  • Geographic Regions
  • Infection
  • Infectious Diseases
  • Proteins
  • Southeast Asia
  • Viral Structures
  • Viruses
  • Yellow Fever
  • Zika Virus

Fields of Study

  • Biology

Readers

  • Vector-Borne Disease and Entomology
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology