Ebola Virus Epidemiology and Evolution in Nigeria

Abstract

Containment limited the 2014 Nigerian Ebola virus disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 cases, and full-length Ebola virus (EBOV) genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data is consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.

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Document Details

Document Type
Technical Report
Publication Date
Oct 04, 2016
Accession Number
AD1012559

Entities

People

  • Adrianne Gladden-young
  • Awa B. Deme
  • Ayorinde James
  • Christian B. Matranga
  • Christopher Tomkins-tinch
  • Daniel J. Park
  • Deborah Ehichioya
  • Dolo Nosamiefan
  • Gustavo Palacios
  • Jason T. Ladner
  • Kendra L. West
  • Kenneth Onyewurunwa
  • Kristian G. Andersen
  • Nicholas E. Oyejide
  • Onikepe A. Folarin
  • Philomena Eromon
  • Sarah M. Winnicki
  • Shirlee Wohl
  • Stephen F. Schaffner
  • Sunday Omilabu

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Cardiovascular Physiological Phenomena
  • Computational Biology
  • Disease Outbreaks
  • Diseases And Disorders
  • Ebola Virus
  • Health
  • Health Services
  • Heart Rate
  • Infection
  • Infectious Diseases
  • Microbiology
  • Pcr Testing
  • Public Health
  • Systems Biology
  • Virus Diseases
  • Viruses

Fields of Study

  • Biology

Readers

  • Business Analytics
  • Molecular Biology and Genetics
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology