Determining Nanoparticle Inhalation Exposure in the Prosthetics Laboratory at Walter Reed National Military Medical Center

Abstract

The increase of wounded warriors has amplified dramatically the need for prosthetics. Generation of particle matter occurred during the four steps of the prostheses manufacturing processes (lamination, plasticization, thermoforming, and grinding). Particle matter from these manufacturing processes are hazardous to human health and suspicion exists that nano-sized aerosols generated during the process will increase this hazard. The author designed a gravimetric and direct reading research study to measure sub-micron particle size distributions in the Walter Reed National Military Medical Center (WRNMMC) prosthetics laboratory. The gravimetric reading consisted of a weight-based measurement, and direct reading used a particle count procedure. Weight analysis did not detect any dust, but X-ray diffraction revealed the presence of quartz, tridymite, and cristobalite. The result obtained from Nanoparticle Emission Assessment Technique showed that each process generated dominantly one type of particle. For particle sizes from 0.3 to 10 microns, no difference was identified between lamination and thermoforming (p=0.189). For nanoparticles, two groups emerged, namely, lamination and plasticization (p=1), as well as grinding and thermoforming, which generated many more nanoparticles (p=1). Plasterization generated the largest particle number concentration for particles between five and ten microns. Grinding and thermoforming generated most of the smaller particle number concentrations, and lamination was the least productive of particle number concentration. Although results were below occupational exposure levels, increases in particle numbers demonstrated additional exposures.

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Document Details

Document Type
Technical Report
Publication Date
Apr 29, 2013
Accession Number
AD1012919

Entities

People

  • Korami Dembele

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Pollution
  • Casualties
  • Chemistry
  • Composite Materials
  • Health Services
  • Hygiene
  • Industrial Hygiene
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Materials Testing
  • Medical Personnel
  • Nanoparticles
  • Particle Size
  • Patient Care
  • Prosthetics
  • Public Health

Fields of Study

  • Materials science

Readers

  • Aerosol Science/Aerosol Physics
  • Neurotrauma and Rehabilitation Medicine.

Technology Areas

  • Biotechnology