Glyco-Immune Diagnostic Signatures and Therapeutic Targets of Mesothelioma

Abstract

The focus of this grant was to investigate immunoprofiles for serum antibodies to aberrant glycans in human and animal models of mesothelioma. This was accomplished using a one of a kind printed glycan array which is at NYU School of Medicine (NYUSoM). It was hoped that these experiments will allow us to diagnose and prognosticate mesothelioma more accurately in the future. We were severely limited by our ability to start the human mesothelioma glycoprofiles as well as the animal profiles due to delivery and set up times for our one of a kind glycomics laboratory at NYUSoM. We summarize our findings in the final report.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2015
Accession Number
AD1012959

Entities

People

  • Margaret Huflejt

Organizations

  • Grossman School of Medicine

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biomedical Research
  • Cancer
  • Cell Line
  • Chemical Synthesis
  • Chemistry
  • Data Analysis
  • Detection
  • Diseases And Disorders
  • Genomics
  • Immunoglobulins
  • Laboratory Animals
  • Lung Cancer
  • Medical Personnel
  • Mesothelioma
  • Neoplasms
  • New York

Fields of Study

  • Biology
  • Medicine

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