Tamoxifen and Aromatase Inhibitors: Cognitive Function in Occupationally Active Breast Cancer Survivors

Abstract

Previous research has suggested that endocrine therapy to inhibit growth of breast cancer tissue is positively associated with cognitive limitations in breast cancer survivors (BCS). Whether this relationship exists in occupationally active survivors is unknown. This study examined endocrine therapy and cognitive function in working BCS, an average of 3 years post-primary treatment. Seventy-seven BCS with past or current exposure to endocrine therapy (tamoxifen or aromatase inhibitors) and 56 BCS with no history of endocrine therapy completed measures of perceived and performance-based cognitive function, physical fatigue, anxiety and depression.

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Document Details

Document Type
Technical Report
Publication Date
May 04, 2010
Accession Number
AD1013394

Entities

People

  • Lynn M. Breckenridge

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Brain
  • Brain Injuries
  • Chemistry
  • Databases
  • Demography
  • Depression
  • Drug Therapy
  • Health Services
  • Information Processing
  • Medical Personnel
  • Psychology
  • Therapy

Fields of Study

  • Psychology

Readers

  • Molecular Biology and Genetics
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.