Social Support, Heart Failure, and Acute Coronary Syndromes: The Role of Inflammatory Markers

Abstract

Heart failure (HF) is a growing clinical and public health problem associated with high morbidity and mortality. Structural and functional social support are implicated in the development and progression of cardiovascular disease (CVD), but not studied as a predictor of incident HF, and the bio-behavioral mechanisms that may underlie this relationship have not been examined. Inflammation, given its role in CVD and HF, may be one promising pathway. Study I used data from the Cardiovascular Health Study (CHS) to prospectively determine the value of structural vs. functional social support as a predictor of incident HF and the mediatingrole of inflammatory markers Interleukin-6 (IL-6) and C-reactive protein (CRP). Study II examined the relationship between specific types of structural and functional social support and inflammatory markers IL-6, CRP, and tumor necrosis factoralpha (TNF-alpha) in a group of patients hospitalized with an acute coronary syndrome.

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Document Details

Document Type
Technical Report
Publication Date
Apr 03, 2008
Accession Number
AD1013778

Entities

People

  • Heather L. Rogers

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Cardiovascular Diagnostic Techniques
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular Surgery
  • Cardiovascular System
  • Health Services
  • Heart Diseases
  • Medical Personnel
  • Myocardial Ischemia
  • Vascular Diseases

Fields of Study

  • Medicine

Readers

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