Cognitive Function and Emotional Status of Middle-aged Chinese Hypertensive Patients Without Detectable White Matter Brain Lesions or Lacunar Infarctions

Abstract

Introduction: Essential hypertension (EH) is associated with cognitive deficits, and higher blood pressure levels have been related to lower levels of cognitive function. Executive functions, speed of processing, memory and attention are especially impacted. Hypertension may affect cognitive function because of pathological physiological changes in the brain (e.g., white matter lesions and/or lacunar infarctions) or behavioral/emotional alterations associated with hypertension (e.g., stress, anxiety, and depression). Objectives: (1) Rule out white matter lesions and lacunar infarctions as necessary causes of cognitive deficits in EH; (2) Examine the role of anxiety and depression as a potential mechanism for the relationship between EH and cognitive function; and (3) Determine socio-demographic and medical moderators of this relationship in individuals without structural brain changes.

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Document Details

Document Type
Technical Report
Publication Date
Aug 30, 2006
Accession Number
AD1014229

Entities

People

  • Heather L. Rogers

Organizations

  • Uniformed Services University of the Health Sciences

Tags

DTIC Thesaurus Topics

  • Alzheimer Disease
  • Brain
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Cerebrovascular Disorders
  • Health Services
  • Information Processing
  • Medical Personnel
  • Psychology
  • Vascular Diseases

Fields of Study

  • Psychology

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