Diagnostic and Treatment Innovations for Mass Casualties

Abstract

It was proposed to define the very early molecular response to soft tissue and vascular injury. That information was applied to develop innovative diagnostic technologies and targeted pharmacologic and genetic therapies. The research strategy consisted of two main goals: 1) quantify the very early inflammatory response to cardiovascular/soft tissue trauma to define an injury severity predictive panel of biomarkers to be incorporated into a sensor 2) design and test novel therapeutic approaches using pharmacologic and gene delivery systems to accelerate and/or stabilize reparative processes leading to greater injury survivability.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2016
Accession Number
AD1016552

Entities

People

  • Allan L. Goldman
  • Brenda R. Flam
  • Joel A. Strom
  • John A. Elliott

Organizations

  • University of South Florida

Tags

Communities of Interest

  • Energy and Power Technologies
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Atmospheres
  • Biological Markers
  • Casualties
  • Contractors
  • Conversion
  • Corpuscular Radiation
  • Department Of Defense
  • Electrons
  • Elementary Fermions
  • Elementary Particles
  • Fermions
  • Gene Delivery
  • Measurement
  • Radiation
  • Soft Tissues
  • Tissues
  • Vascular System Injuries

Fields of Study

  • Medicine

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Software Engineering

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech