High Spatiotemporal Resolution Prostate MRI
Abstract
Prostate cancer (PCa) is the second leading cause of cancer death in men. However, when detected and treated promptly the five-year relative survival rate approaches 100 . The overall purpose of this project is to develop improved means using MRI for detecting prostate cancer with the potential for differentiating disease aggressiveness. The hypothesis is that dynamic whole-volume contrast-enhanced perfusion imaging of the prostate gland can be performed with 1 mm isotropic spatial resolution and 2 sec frame times, providing an order of magnitude improvement over current techniques. The specific aims are: (i) to develop an MRI acquisition technique for time-resolved 3D MRI of the prostate, (ii) to develop a fundamentally new coil element family having variable sensitivity along the superior-to inferior direction, (iii) to incorporate partial Fourier and acceleration methods into high speed reconstruction to provide high quality 3D images in real time at frame times of 2 sec or less.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2016
- Accession Number
- AD1017908
Entities
People
- Stephen J Riederer