Acquisition of a Laser Scanning Confocal Microscope to Examine CNS Activity of Antidotal Oximes and to Enhance Undergraduate Research Training Across the Sciences
Abstract
The project utilized funding to acquire a confocal laser scanning microscope (Olympus FV1200) to support research examining the ability of antidotal oximes to rescue organophosphate (OP)-induced CNS toxicity and training across the sciences and social sciences at Whittier College. In particular the acquisition of the FV 1200 allows the PI, Dr. Erica Fradinger, to extend her research of blood-brain-barrier (BBB) penetrant oxime antidotes to investigate their effects on both OP-induced PNS and CNS toxicity. Additionally, this instrument will support interdisciplinary research activities in the Center for Science, Health, and Policy, support pedagogical advances, and expose students to cutting edge technologies. Users come from the biology, chemistry, physics, and psychology departments. The requested FV 1200 expands the research capacity of four faculty, enhance eight courses in the biology, chemistry and psychology departments, and expand the capstone research projects of students across the sciences. While the research and teaching interests of the participants are diverse, all are able to use the equipment to detect, quantify, or visually localize gene expression products to study protein function at the cellular and sub-cellular levels.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 15, 2016
- Accession Number
- AD1017967
Entities
People
- Erica Fradinger
Organizations
- Whittier College