Metagenomic Sequencing for Detection of Non-Traditional Biological Agents: Synthetic Constructs, Genetically Modified Organisms, and Emerging Threats

Abstract

Non-traditional biological threat agents could potentially by-pass or defeat current detection technologies. The goal of this project is to assess the feasibility of using present sequencing Bioinformatics technology for the identification of genetically modified organisms, identify any shortcomings and provide the input data for the development of a strategy for the ultimate discovery pipeline necessary for new biological agents.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 31, 2013
Accession Number
AD1018057

Tags

DTIC Thesaurus Topics

  • Ammonium Compounds
  • Anti-Bacterial Agents
  • Bacteria
  • Bacterial Infections
  • Biological Factors
  • Biological Toxins
  • Chemistry
  • Environment
  • Escherichia Coli
  • Genetic Engineering
  • Genetically Modified Organisms
  • Microbiomes
  • Mycobacterium Tuberculosis
  • Quality Control
  • Sequence Analysis
  • Staphylococcus Aureus
  • Synthetic Biology

Fields of Study

  • Biology

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Sensor Fusion and Tracking Systems.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology