Silver Nanoparticle Storage Stability in Aqueous and Biological Media

Abstract

Silver has antimicrobial effects against a broad spectrum of bacteria and has been successfully incorporated into wound treatments to reduce infections. Dressings and implant coatings are being developed which integrate silver nanoparticles (AgNPs) for their long-term antimicrobial properties. The medium components that interact with the nanoparticles play asignificant role in the destabilization of the nanoparticle over time. Although this interaction plays an important role in thelong-term use and storage of AgNPs, there are few reports describing the stability and storage of the nanoparticles. The objective of this technical report was to evaluate the stability of silver nanoparticles stored for 14 days in different aqueousand biological media. Silver nanoparticles were stable for 14 days in de-ionized water without significant changes to size or morphology.

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Document Details

Document Type
Technical Report
Publication Date
Jun 22, 2015
Accession Number
AD1019362

Entities

People

  • Mauris N. Desilva
  • Natalie A. Forbes
  • Tony T. Yuan

Organizations

  • Naval Medical Research Unit—San Antonio

Tags

DTIC Thesaurus Topics

  • Alanine
  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Burns
  • Culture Media
  • Culture Techniques
  • Electron Microscopy
  • Health Services
  • Infection
  • Materials
  • Medical Personnel
  • Metallic Nanoparticles
  • Nanoparticles
  • Particles
  • Spectra
  • Transmission Electron Microscopy

Readers

  • Atmospheric Science / Meteorology, specifically Wind Wave Turbulence.
  • Microbial Pathology
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology