A Cell-Based Approach to Early Pancreatic Cancer Detection
Abstract
During this reporting period, we succeeded in building a device (TEMPO) that can enrich circulating pancreatic tumor cells from mouse blood by depleting the sample of white blood cells (WBCs). Furthermore, the RNA profile of these cells can be assessed by fluorescence in situ hybridization (FISH) and visualized on the same device. Using the device, this entire process can be conducted in a matter of hours without specialized equipment and a standard fluorescent microscope. These studies set the state for further experiments with clinical samples from pancreatic cancer patients.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2016
- Accession Number
- AD1020613
Entities
People
- Ben Z Stanger