Development and Translation of Hybrid Optoacoustic/Ultrasonic Tomography for Early Breast Cancer Detection

Abstract

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging modality that combines high ultrasonic resolution with strong optical or microwave contrast, and represents a highly promising biomedical imaging modality [1,2,3]with a great potential for early breast cancer detection and subsequent management. On the other hand, ultrasound computed tomography (UST) can provide high-resolution anatomical images of breast lesions based on three complementary acoustic properties (speed-of-sound (SOS), attenuation, reflectivity). The broad objective of the proposed research is to develop an optimized system design and associated image reconstruction algorithms for a hybrid three-dimensional (3D) breast imaging system that combines OAT and UST. This system will provide co-registered functional and anatomical information without the need for breast compression, ionizing radiation, or contrast agents, which will result in a highly effective and affordable 3D imaging method.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2015
Accession Number
AD1020705

Entities

People

  • Fatima Anis

Organizations

  • University of Washington

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acoustic Propagation
  • Acoustic Properties
  • Acoustic Waves
  • Acoustics
  • Breast Cancer
  • Computational Science
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Medical Personnel
  • Optical Properties
  • Optics
  • Photoacoustic Tomography
  • Three Dimensional
  • Tomography
  • Two Dimensional
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Integrated Circuit Design and Technology.
  • Medical Imaging.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech