An Unconventional Approach To Reducing Retinal Degeneration After Traumatic Ocular Injury
Abstract
This project seeks to image abnormal retinal pericyte vasospasms after ocular trauma in mice, and their relationship to: retinal macrophage activity, and oral administration of L-Arginine. In the first year we overcame significant technical difficulties with in vivo fluorescent labeling of retinal pericytes, using both fiber-optic confocal and multiphoton microscopic imaging techniques, and we successfully established the imaging protocol for in vivo retinal pericyte imaging with simultaneous measurement of microspasms in retinal capillary beds.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2016
- Accession Number
- AD1022095
Entities
People
- Stephen L. Macknik
Organizations
- SUNY Downstate Health Sciences University