Novel Treatment for Patients with Traumatic Brain Injury (TBI)

Abstract

Systemic hypotension independently increases morbidity and mortality after traumatic brain injury. The goal of all treatments is avoid hypotension and maintain cerebral perfusion. If this cannot be achieved with fluids, pressers are required. Unfortunately, refractoriness and other adverse events are common with standard of care catecholamine pressers and there are no FDA-approved alternatives if refractoriness develops or severe adverse events occur during treatment of a brain injured patient. This project was designed to provide an alternative and thereby extend the existing capability of physicians to treat patients with life threatening brain injury.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2016
Accession Number
AD1022353

Entities

People

  • Kenneth G. Proctor

Organizations

  • University of Miami

Tags

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Brain Injuries
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Health Services
  • Hemorrhagic Shock
  • Medical Personnel

Fields of Study

  • Medicine

Readers

  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.
  • Trauma or Military Medicine