Evaluation of 10 Jet Fuels in the Salmonella-Escherichia coli Mutagenicity Assay

Abstract

The focus of this study was to evaluate the toxicity of ten jet fuels of interest to the United States Department of Defense. Specifically, this study aimed to determine the potential of the jet fuels to induce DNA damage that may lead to genetic mutations. All of the jet fuels tested were considered to be negative for mutagenicity in the bacterial reverse mutation assay using Salmonella and E. coli strains. Based on the parameters used in this in vitro study, Citgo JP8 (POSF 4658), Valero 25 Aromatic JP8 (POSF 8457), KiOR Hydrotreated Kerosene/Bio-Kerosene (POSF 10327), ARA ReadiJet (POSF 10328), Amyris Farnesane (POSF 10329), Virent HDO-SK (POSF 10330), TS-1 (Specification number 10227-86), Gevo 7695 with JP8 additives (POSF 7699), Gevo 10262 with JP8 additives (POSF 10263), and Swedish Biofuel 7633 with JP8 additives (POSF 8452) are considered to be nonmutagenic.

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Document Details

Document Type
Technical Report
Publication Date
Sep 07, 2016
Accession Number
AD1023715

Entities

People

  • David R. Mattie
  • Karen L. Mumy
  • Nathan M. Gargas

Organizations

  • Naval Medical Research Unit Dayton

Tags

DTIC Thesaurus Topics

  • Additives (Chemicals)
  • Bacteria
  • Department Of Defense
  • Escherichia
  • Escherichia Coli
  • Governments
  • Histidine
  • Mutagenicity Tests
  • Mutations
  • Sodium Azides
  • Sodium Compounds
  • Specifications
  • Standards
  • Statistical Analysis
  • Toxicity
  • Tryptophan
  • United States Government

Readers

  • Immunology and Pathology
  • Petroleum Engineering

Technology Areas

  • Biotechnology