Pilot Comparisons of Temporary Open Revascularization Using Stent Grafts vs. Standard Shunts in a Sheep (Ovis aries) Model
Abstract
Objectives: Pilot study and development of an experimental model to test and compare the performance of endovascular stent-graft as an arterial shunt. Methods: Developed a model of vascular shunting in an Ovine model. Develop methods of observing and measuring the performance of these vascular shunts. Results: Exposure and placement of vascular stent-grafts and shunts into the common carotid artery was feasible. Stent-graft and shunt performance could be observed through pressure monitoring, duplex and contrast angiography. Consistently observed low resistance flow patterns, the highly mobile nature of the area and early graft failure during model development raised the question of the appropriateness of this anatomic region for testing of stent-graft/shunts to be used to treat peripheral vascular injury. Conclusion: Study of endovascular stent-grafts for use as a vascular shunt is feasible. Graft performance may be measured through pressure monitoring, duplex, and angiography. Use in the carotid artery may confound results and limit relevance to proposed use in the management of peripheral vascular injury.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 14, 2016
- Accession Number
- AD1023821
Entities
People
- James Sampson
Organizations
- David Grant USAF Medical Center