Beneficial and Deleterious Bacterial - Host Interactions in Chronic Wound Pathophysiology

Abstract

Chronic wounds represent a major health and financial burden. Although incredible advancements in wound management have been made in the last decade, the incidences of chronic wounds continue to increase due to a rise in biofilm-associated infections. The presence of biofilm causes chronic inflammation, leading to impaired healing rates and host mortality. This review describes the deleterious bacterialhost interactions, as well as the beneficial role of pH and probiotics in chronic wound infections.

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Document Details

Document Type
Technical Report
Publication Date
Apr 02, 2015
Accession Number
AD1023945

Entities

People

  • Chase Watters
  • Kendra P. Rumbaugh
  • Tony T. Yuan

Organizations

  • University of Texas at Austin

Tags

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Bacteria
  • Bacterial Infections
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Debridement
  • Dermatologic Agents
  • Foot Diseases
  • Health Services
  • Immune System
  • Infection
  • Lymphocytes
  • Medical Personnel
  • Pathogenic Bacteria
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology and Pathology
  • Microbial Pathology

Technology Areas

  • Biotechnology