Prevention of Blast-Related Injuries

Abstract

This report covers work done on blast testing of live anesthetized swine and on unembalmed cadavers. A detailed histological study of blast-exposed swine brain showed that there was damage to both the axons and the neuron cell bodies in the form -APP immunoreactivity and other tests, suggesting that the mechanism of injury may be different from that of blunt impact. We have also developed computer models of the swine and human brain and are in the process of validating them against the acquired experimental data. It is proposed that future research concentrate on seeking injury mechanisms to brain cells caused by a pressure wave.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2016
Accession Number
AD1023992

Entities

People

  • Albert I. King
  • John Cavanaugh
  • King Yang
  • Liying Zhang
  • Xin Jin

Organizations

  • Wayne State University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Brain
  • Brain Injuries
  • Cardiovascular Physiological Phenomena
  • Explosives
  • Health Services
  • Medical Personnel
  • Test Methods
  • Traumatic Stress Disorder
  • Wave Propagation

Readers

  • Infectious Disease/Epidemiology
  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.