A Randomized, Controlled Trial of Meditation Compared to Exposure Therapy and Education Control on PTSD in Veterans
Abstract
This study consists of a comparative effectiveness trial of Transcendental Meditation (TM) compared to Prolonged Exposure (PE) and education control (EC) groups in Veterans diagnosed with clinically significant PTSD by way of a validated structured interview methodology over a treatment period of three months. Two hundred and ten veterans will participate in this three-arm trial. Testing will be conducted at 0 and 3 months for PTSD symptoms, psychological distress, depression, quality of life, behavioral factors, and physiological/biochemical mechanisms using validated interview, self-report, and biological measures. Recruitment began in June of 2013. We hypothesize that TM will be non-inferior to PE on the primary outcome of the study and superior to EC on PTSD study outcomes. This will be a multidisciplinary, collaborative research project comprising investigators from the San Diego VA Healthcare System, the University of California at San Diego and Maharishi University of Management Research Institute. Given a sample of 210 patients, an alpha level of .05 for declaring statistical significance, equal standard deviations, and an attrition rate of 20%, estimated power levels are >-.90.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2016
- Accession Number
- AD1024768
Entities
People
- Thomas Rutledge