Development of Biomarkers for Assessing In Situ RDX Biodegradation Potential

Abstract

The objective was to identify the microorganisms and genes responsible for the biodegradation of RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) in mixed microbial communities using stable isotope probing, quantitative PCR and high throughput sequencing. The research targeted RDX biodegradation in mixed community samples, as these microbial communities are more representative of those at contaminated sites. The research involved four major projects, the first of which was a literature review. The second task examined the RDX degrading communities in four different soil slurries. The third task examined the microorganisms involved in RDX biodegradation from surface soils from a detonation area at a Navy Base. The fourth task investigated the microorganisms and functional genes (xenA, xenB and xplA) linked to RDX biodegradation at two Navy sites. Several key microorganisms were associated with RDX removal in these mixed communities. These phylogenetic and functional biomarkers will be useful to determine the biological potential for RDX degradation across sites.

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Document Details

Document Type
Technical Report
Publication Date
Jun 10, 2016
Accession Number
AD1025345

Entities

People

  • Alison M Cupples

Organizations

  • Michigan State University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bacteriology
  • Betaprotobacteria
  • Biodegradation
  • Chemical Synthesis
  • Chemistry
  • Ecology
  • Environmental Pollution
  • Environmental Protection
  • Gammaproteobacteria
  • Microbiology
  • Microbiomes
  • Microorganisms

Fields of Study

  • Biology
  • Environmental science

Readers

  • Groundwater Contamination Remediation.
  • Microbial Pathology
  • Rocket Propulsion.

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation