A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

Abstract

This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response of field-effect-transistor (FET)-based biosensors. The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential advantage of high density and low noise performance. The biosensor shows a current response of 5.74 decades per pH for pH detection, which is 2.5 105 times larger than that of a single SiNW sensor. In addition, we demonstrate charged polymer detection using the biosensor, with a high current change of 4.5 105 with a 500 nM concentration of poly(allylamine hydrochloride).In addition, we demonstrate a wide dynamic range can be obtained by adjusting the liquid gate voltage. We expect that this biosensor will be advantageous and practical for biosensor applications which requires lower noise, high speed, and high density.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jul 21, 2015
Accession Number
AD1025708

Entities

People

  • Bongsik Choi
  • Dae H. Kim
  • Dong M. Kim
  • Jaeman Jang
  • Jee-yeon Kim
  • Jieun Lee
  • Jinsu Yoon
  • Sung-jin Choi
  • Yang-kyu Choi

Organizations

  • Yale University

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical

DTIC Thesaurus Topics

  • Amplification
  • Amplifiers
  • Biological Detection
  • Biosensors
  • Buffers (Chemistry)
  • Detection
  • Detectors
  • Dynamic Range
  • Electrical Engineering
  • Electron Microscopes
  • Engineering
  • Field Effect Transistors
  • High Density
  • Nanowires
  • Noise
  • Scanning Electron Microscopes
  • United States

Readers

  • Electrochemical Surface Science
  • Integrated Circuit Design and Technology.
  • Nanoscale Plasmonic Nanotechnology

Technology Areas

  • Biotechnology