Hadamard Transform Time-of-Flight Mass Spectrometry
Abstract
Mass spectrometry (MS) is a powerful analytical tool for determining the structural and chemical identities of a broad array of analytes that can be converted to gas-phase ions. MS possesses the advantages of rapid data acquisition, sensitivity, large dynamic range, and selectivity. Though different instruments employ different specific measurement principles, all mass spectrometers share the common goal of measuring parameters that can be converted to a histogram of mass-to-charge ratios. This goal is achieved through the manipulation and monitoring of ions exposed to known electric and/or magnetic fields . Unlike many other analytical techniques, mass spectrometry is completely general: any chemical species that can be made into a stable gas-phase ion can be analyzed. Ion source technologies, methods to produce gas-phase ions, have advanced rapidly. These new methods enable gas-phase ion generation from most types of chemical samples from both the solution-phase and the solid-phase without the need for any labeling or chemical derivatization.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 05, 2010
- Accession Number
- AD1026366
Entities
People
- Griffin K. Barbula
- Matthew D. Robbins
- Richard Perry
- Richard Zare
Organizations
- Yusuf Hamied Department of Chemistry