Mobile, Multi-modal, Label-Free Imaging Probe Analysis of Choroidal Oximetry and Retinal Hypoxia

Abstract

Coherent anti-stokes Raman spectroscopy (CARS) can be used to detect differences in the oxygen content in aqueous hemoglobin solutions. Our current setup is not ideal for accurately calibrating these measurements, but changes in the microscope setup and in the addition of gaseous oxygen to the physical sample are promising next steps.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1028470

Entities

People

  • Jared C. Gilliam
  • Stephen T. Wong

Organizations

  • Houston Methodist Research Institute

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biological Markers
  • Biomedical Research
  • Blast Injuries
  • Eye Injuries
  • Fluorescence
  • Health Services
  • Hemoglobin
  • Imaging Techniques
  • Measurement
  • Microscopes
  • Proteins
  • Quarantine
  • Raman Scattering
  • Raman Spectroscopy
  • Spectroscopy
  • Technology Transfer

Fields of Study

  • Physics

Readers

  • Cardiovascular Physiology
  • Nanoscale Plasmonic Nanotechnology
  • Optical Physics and Photonics.