A New Tool for Local Manipulation of Neuronal Micro-Circuitry with Ions and Force

Abstract

Our goal is to compute the complete functional connectivity map of a living neuronal network spontaneously assembled in culture and determine the utility of its information content as a synthetic memory trace. To date no functional connectivity map exists for living neurons at the resolution proposed here. In fact, a quantitative model of the microcircuitry at the level of the single synapse remains inaccessible with current technology. We will develop a deep learning module for diagnosing MEA patterns and establish a complete connectivity map for hippocampal cultured neurons.

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Document Details

Document Type
Technical Report
Publication Date
Feb 07, 2017
Accession Number
AD1028574

Entities

People

  • Kenneth S. Kosik

Organizations

  • University of California Regents

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  • Biomedical

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  • Biology

Readers

  • Computer Science.
  • Neural Network Machine Learning.
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Technology Areas

  • AI & ML
  • AI & ML - Neural Networks