Hemorrhage Control for Major Traumatic Vascular Injuries

Abstract

The objective of this proposed study is to systematically define the clinical and logistical issues surrounding traditional open vascular surgery and catheter-based hemorrhage control. The hypothesis is that minimally invasive, device-driven and expert-led NCTH control techniques improve survival compared to traditional open vascular surgery. This project will achieve the following aims: 1) Determine current practice patterns for the treatment of patients with NCTH among 4 clinical sites using a retrospective study design (Phase 1a); 2)Conduct a 2-day Delphi Panel meeting of military and civilian experts to gain consensus regarding anatomic, technology, credentialing, competency, and training issues for catheter-based hemorrhage control (Phase 1b); 3) Conduct a prospective 4-site observational study to test the hypothesis that less-invasive device-driven and expert-led hemorrhage control techniques are associated with improved survival in NCTH patients and strengthen the evidence base to inform future development of catheters, devices, and training required for surgeons for catheter-based hemorrhage control (Phase 2). At the end of Y2, the retrospective study has been completed, the Delphi Meeting has been held and a manuscript describing the results has been drafted. In addition, the prospective study will be initiated in Y3Q1 and regulatory approvals are in place or pending at all sites.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1029673

Entities

People

  • John B Holcomb

Organizations

  • University of Texas Health Science Center at Houston

Tags

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Health Services
  • Hemorrhagic Shock
  • Medical Personnel
  • Veins

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Instructional Design and Training Evaluation.
  • Trauma Surgery or Emergency Medicine.