Biocompatible and Biomimetic Self-Assembly of Functional Nanostructures

Abstract

Our bio-compatible and biomimetic research has been focused on the use of living cells, biomolecular interfaces and bio-mimetic processes to direct the formation of new classes of complex, symbiotic, hierarchical materials with life-like structure and functionality. This aim is predicated on two principal goals: 1) use of living/fixed cells to direct the formation of new classes of complex, hierarchical materials with lifelike (or new) structures and functionality, evidenced by the preservation of cell and organism structure in silica with sub 10-nm fidelity through a reaction with silicic acid, and transformation of these replicates to carbon or carbon/silica hybrids, enabling multiscale imaging without loss of resolution and 2) use of self assembly to create engineered nano-to-microscale environments to direct new cellular behavior and confer enhanced biomolecular stability.

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Document Details

Document Type
Technical Report
Publication Date
Mar 15, 2017
Accession Number
AD1030033

Entities

People

  • C. Jeffrey Brinker

Organizations

  • University of New Mexico

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Cells
  • Cellular Structures
  • Chemical Synthesis
  • Chemistry
  • Culture Techniques
  • Engineered Materials
  • Health Services
  • Material Degradation Processes
  • Materials
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Medical Personnel
  • Nanomaterials
  • Nanoparticles
  • Synthetic Biology
  • Three Dimensional

Readers

  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology
  • Microelectronics