BioProgrammable One, Two, and Three Dimensional Materials

Abstract

The MURI team has used biomolecules (such as DNA or peptides) to assemble nanoparticles into highly ordered one-, two-, or three dimensional architectures. The Mirkin group has used DNA-functionalized nanoparticles as programmable atom equivalents (PAEs) as material synthons to synthesize hundreds of different crystal structures. The Macfarlane group developed methods to combine bottom-up DNA directed assembly with electron beam lithography to simultaneously control material structure at the nano- and macroscopic length scales. The Nguyen group has synthesized and assembled small molecule-DNA hybrids (SMDHs) as part of programmable atom equivalents. The Rosi group identified design rules for using peptide constructs to direct rational assembly of inorganic nanoparticles into ordered hierarchical nanoparticle superstructures, including hollow spherical structures and 1-D helical nanoparticle arrays exhibiting strong plasmonic chiroptical response. Theoretical studies as well as various characterization techniques were studied in conjunction with all of the abovementioned experimental approaches to construct new materials with biomolecule-functionalized building blocks. The Schatz group developed electrodynamics models of plasmonic superlattices to identify unique optical behavior of these materials, including negative permittivity, Fabry-Perot resonances, and nonreciprocal properties. The Olvera group predicted the shape of single crystals of DNA functionalized nanoparticles and their nucleation behavior. The Bedzyk group utilized in-situ X-ray scattering and spectroscopy to develop fundamental understanding of PAE constructs, from their synthesis and electrostatic environment, to inter-PAE interactions that affect programmable assembly. As a whole, the MURI team synthesized, measured, and evaluated a set of new materials with specific properties by design.

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Document Details

Document Type
Technical Report
Publication Date
Jan 18, 2017
Accession Number
AD1030301

Entities

People

  • Chad Mirkin
  • George C. Schatz
  • Michael Bedzyk
  • Monica Olvera de la Cruz
  • Nathaniel L Rosi
  • Robert J Macfarlane
  • SonBinh Nguyen

Organizations

  • Northwestern University

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical

DTIC Thesaurus Topics

  • Chemistry
  • Crystal Structure
  • Crystallography
  • Crystals
  • Health Services
  • Material Degradation Processes
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Materials Testing
  • Metallic Nanoparticles
  • Nanomaterials
  • Nanotechnology
  • Optical Properties
  • Surface Plasmon Resonance

Readers

  • Nanocomposite Materials Science
  • Quantum Dot Semiconductor Device Photonics and Graphene Optoelectronic Materials and THz Physics.

Technology Areas

  • Biotechnology
  • Directed Energy
  • Microelectronics