Skeletal and Clinical Effects of Exoskeletal Assisted - Gait

Abstract

The purpose of this project is to study the effects on bone health of exoskeleton-assisted gait in individuals with a complete spinal cord injury. Advanced biomechanical models of human locomotion are utilized to estimate the mechanical effects of the dynamic loading of the bone structures that takes place during exoskeleton-assisted gait. The estimated maximum energy equivalent strain is studied as a potential proxy of bone adaptation and correlated with high-resolution peripheral quantitative computed tomography data and with clinical measures (e.g. biomarkers of inflammation such as C-reactive protein and IL-6) that are collected longitudinally. The research team has developed advanced biomechanical models to study the biomechanics of exoskeleton-assisted gait and derive estimates of loads applied to the bones. The research team continues to recruit study volunteers.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2016
Accession Number
AD1031287

Entities

People

  • Karen L Troy
  • Leslie Morse
  • Paolo Bonato

Organizations

  • Spaulding Rehabilitation Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomechanical Phenomena
  • Biomechanics
  • Biomedical Engineering
  • Data Analysis
  • Exoskeleton
  • Health Services
  • Lower Extremity
  • Mechanical Properties
  • Medical Personnel
  • Motion Capture
  • Professional Development
  • Spinal Cord
  • Spinal Injuries
  • Technology Transfer
  • Tomography
  • Volunteers
  • X-Ray Computed Tomography

Readers

  • Immunology and Pathology
  • Neurotrauma and Rehabilitation Medicine.
  • Robotics and Automation.