Tu(r)ning weakness to strength: Mechanomutable bioinspired materials

Abstract

They used a combination of multiscale modeling and experimental synthesis to understand the behavior of this heterologous-expressed protein from the nanoscale to the macroscale. They built a bottom-up molecular-based model, which includes electronic -based density functional theory calculations, atomistic simulation of the nanoscale properties with replica exchange molecular dynamics, and an elastic network model for describing the macroscale behavior at different pHs. This multiscale modeling supports the experimental synthesis of a photo-crosslinked Nvjp-1 hydrogel by proving both the nanoscale mechanisms and mechanical behavior predictions.

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Document Details

Document Type
Technical Report
Publication Date
Apr 03, 2017
Accession Number
AD1032223

Entities

People

  • Markus J. Buehler

Organizations

  • Massachusetts Institute of Technology

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical
  • Cyber

DTIC Thesaurus Topics

  • Additive Manufacturing
  • Biomaterials
  • Chemical Engineering
  • Chemistry
  • Composite Materials
  • Fish
  • Manufacturing
  • Materials
  • Materials Laboratories
  • Materials Science
  • Mechanical Engineering
  • Mechanical Properties
  • Mechanics
  • Military Research
  • Multiscale Modeling
  • Nanotechnology
  • Systems Biology

Readers

  • Computational Modeling and Simulation
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology
  • Microelectronics