Risk Stratification of Stress Fractures and Prediction of Return-to-Duty

Abstract

This second annual report reviews progress towards completing each of our three study tasks. Major accomplishments include IRB renewal for all study protocols, hiring and training of new staff at MGH, as well as the completing subject enrollment for Task 1 and continuing enrollment for Task 3. In study Task 1 we aim to determine the sex- and race-ethnicity-specific bone traits that may contribute to stress fracture risk in military recruits. We are ahead of schedule by increasing our study size and completing study enrollment, with 185 subjects enrolled (n= 50 White women, 50 White men, 51 Black women, 34 Black men). Data analysis and manuscript preparation are underway. In study Task 2 we aim to quantify changes in bone structure and bone metabolism in recruits before and after Basic Combat Training (BCT). Enrollment and data collection are complete, and data analysis is ongoing. Finally, for study Task 3 we aim to characterize recovery and predict bone-healing trajectories and develop return-to-duty guidelines. We hypothesize that changes in bone health during recovery from stress-fracture injury can be quantified and used to develop evidence-based RTD. Enrollment is underway, with 13 women with recent stress fracture enrolled.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2016
Accession Number
AD1033061

Entities

People

  • Kristin Popp
  • Mary L. Bouxsein

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • African Americans
  • Biomedical Research
  • Bone Fractures
  • Data Analysis
  • Data Science
  • Education
  • Health Services
  • High Resolution
  • Institutional Review Board
  • Medical Personnel
  • Metabolism
  • Musculoskeletal Physiology
  • Predictive Modeling
  • Recovery
  • Statistical Analysis
  • Training
  • X-Ray Computed Tomography

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